Tissue-specific gene therapy directed to tumor angiogenesis
نویسندگان
چکیده
منابع مشابه
Gene therapy for ocular angiogenesis.
Ocular neovascularization is a central feature of diabetic retinopathy and age-related macular degeneration. These conditions are the major causes of blindness in the developed world. Current treatments are of limited efficacy and associated with significant adverse effects. Characterization of the molecular and cellular events involved in angiogenesis has led to the identification of a number ...
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Dale J. Voeks1, Gary A. Clawson2, and James S. Norris1 1Medical University of South Carolina, Charleston, SC; 2Penn State University, Hershey, PA __________________________________________________________________________________________________ Correspondence: Dr. James S. Norris, Department of Microbiology and Immunology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, Sou...
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Background and Aims: An impairment of expression in MLL2 gene involved in histone methylation induces alteration in the methylation patterns at enhancers and causes several cancers including colon cancer. In this study, MLL2 expression was evaluated in North West of Iran. Materials and Methods: To evaluate the MLL2 expression in patients with colon cancer, 25 tumor samples and 25 samples of tu...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2001
ISSN: 0969-7128,1476-5462
DOI: 10.1038/sj.gt.3301472